For the nightcap on Tuesday, the Reds -- who prevailed, 4-2, in Game 1 -- called up left-hander David Holmberg from Triple-A Louisville to face the Cubs. Holmberg will be making his second career Major League start, and his debut for Cincinnati. He went 0-4 with a 5.28 ERA in 10 starts for Louisville, but since coming off the disabled list on June 11 following a left shoulder injury, he posted a 1.71 ERA in five games.
The Cubs will counter with fellow lefty Tsuyoshi Wada, who will be making his Major League debut. Wada pitched well for Triple-A Iowa, going 9-5 with a 2.66 ERA in 17 appearances (16 starts), striking out 105 in 101 2/3 innings. Wada was in the Orioles' system from 2012-13, and had Tommy John surgery in May 2012.
"In the spring, he was elevated a little bit, outside of the zone, and he's been pitching down in the zone, both sides of the plate, and has been mixing his pitches and been very effective, which is good to hear," Cubs manager Rick Renteria said of Wada.
Cubs: Beeler, Hendricks to start Wednesday and Thursday
With rain in the forecast for Monday and Tuesday in Cincinnati, the Cubs waited until after Monday's series opener to announce their starters for the final two games of the five-game series against the Reds, just in case Monday's game was postponed.
Though there was a 21-minute rain delay that stopped play, the game resumed and was completed with the Reds winning, 9-3.
After trading Jeff Samardzija and Jason Hammel to the A's, Chicago had to fill its spots in the rotation, announcing that right-handers Dallas Beeler and Kyle Hendricks would start Wednesday and Thursday, respectively.
Beeler made his big league debut earlier this season for Chicago, being called up from Triple-A Iowa to start the first game of a doubleheader against the Nationals on June 28. He tossed six innings and allowed an unearned run on four hits, walking three and striking out six.
Hendricks was pulled from his start for Triple-A Iowa after two innings on Sunday, and was 10-5 with a 3.59 ERA in 17 starts in Triple-A.
Reds: Votto heads back to DL
First baseman Joey Votto was placed on the 15-day disabled list on Tuesday, retroactive to Sunday, for the same injury that landed him on the DL earlier this season, a distal quad strain in his left knee.
"We did a full workup on Joey yesterday," manager Bryan Price said before Tuesday's day-night doubleheader against the Cubs. "There's definitely more soreness and a continued issue with it. It's something that he's just not going to be able to play on.
"Our plan of attack will be to do everything we can to get him back to be able to play over the course of the year. I don't have a timetable on how long that will be, but the goal is to get him back and able to help us before the year is out."
Price added that "it's probably not a 10- to 15-day issue," indicating Votto will likely be out longer.
• Tuesday's twin bill is the third for the Cubs this season (April 16 against the Yankees in New York, June 28 against the Nationals at Wrigley Field). It's the second for the Reds (May 15 against the Padres at Great American Ball Park).
Manny Randhawa is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.