Thanks to the Astros' migration to the American League, the Royals and Phillies will begin their Interleague schedule earlier than ever, with the clubs meeting on Friday to begin a three-game weekend set at Citizens Bank Park.
On the mound for Kansas City will be right-hander Wade Davis, making his Royals debut after being acquired from Tampa Bay in December in the seven-player deal that included James Shields and Elliot Johnson.
Davis enjoyed plenty of success throughout Spring Training, tying for the Cactus League lead in wins, with four, and allowing just two earned runs over 14 innings.
Davis, who spent the 2012 season in the Rays' bullpen, faced the Phillies last June in Philadelphia, surrendering three runs on three hits and two walks over 2 2/3 innings of relief.
He will have to hit with Friday's Interleague contest at a National League park, something he has been successful at doing in the past. In just five career at-bats, he has a pair of hits to his credit.
"I've always enjoyed hitting," Davis said. "Not necessarily because I enjoyed swinging the bat, but understanding why my hands couldn't hit certain pitches and stuff like that helps you understand your opponents' swings -- why they work one way and why they can't hit certain pitches."
Opposing Davis will be Kyle Kendrick, who went 11-12 with a 3.90 ERA in 2012. In his final start of the spring, the 28-year-old right-hander allowed five runs over three innings against the Blue Jays.
Royals: Dyson fills in for Cain
The Royals' first lineup change came on Thursday, when Jarrod Dyson replaced Lorenzo Cain as the center fielder and batted eighth against the White Sox. The move signals the start of a trend Kansas City will look to continue throughout the year.
"My plan going in was to play Cain about five days a week, keep his legs underneath him and keep Dyson involved," manager Ned Yost said. "I've got a pretty versatile bench, and I want to try to keep them all involved. I don't want them sitting for long periods of time without playing."
Dyson drove in the first run of the afternoon on Thursday with a groundout in the fifth inning to put the Royals on top.
In the first two games at Chicago, only Miguel Tejada came off the bench. He pinch-hit (and walked) for Chris Getz and played two innings at second base.
Phillies: Brown hits his stride
Domonic Brown carried his good Spring Training into the first three games of the season, collecting four hits in his four bats to go along with a walk as well.
"He looks good," manager Charlie Manuel said. "He got a couple of hits Wednesday off a lefty. He looks good. Yeah."
Conversely, Ryan Howard is just 1-for-12 following a good spring.
"That's baseball," Manuel said. "That's the way it goes. You don't take nothing for granted, and you play every day. That's what it is."
• By breaking into the win column on Thursday, the Royals avoided their first 0-3 start since 2001, when the Yankees swept them to open the season.
• The last two times the Phillies started 0-2, as they did this season, they went on to reach the World Series (2008 and 2009).
Tyler Emerick is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.